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Genetic treatments

To fulfil your dream of becoming a mom!

Preimplantation Genetic Diagnosis (PGD)

Preimplantation Genetic Diagnosis (PGD) is a technique that allows a detailed analysis of the embryo before being transferred to the maternal uterus. This makes it possible to transfer embryos free of any hereditary disease. It is recommended as long as the patient has an optimal response to ovarian stimulation and the genetic disease under study is within the legal limits of techniques of assisted human reproduction.

The designed technique is only to be applied in case of the detection of serious hereditary diseases in an early appearance and in case there is no susceptible to postnatal curative treatment. This in order to select embryos that are not suitable for transfer. Likewise, this technique serves as well for the detection of other alterations that may compromise the viability of the embryo.

Once the first phases of the diagnosis have been carried out, such as embryo formation and embryo biopsy, we proceed with the different genetic analyses. It is at this point that the thorough study of hereditary diseases becomes fundamental.

Study of monogenic genetic diseases


This analysis consists of the study of the embryo before being transferred in order to ensure the absence of a possible mutation. In this way the disease under study will not appear with the offspring of the affected family. In order to carry it out, it is necessary to undergo an examination of the couple and certain family members to determine the existing mutations.

Subsequently, the selected embryos are stored in a biological incubator under controlled conditions of temperature, oxygenation and humidity, similar to those of the fallopian tubes. Under these conditions the embryos are kept in cultivation for a period of one to three days, before carrying out the transfer between four and six days after the ovarian puncture.

The study of monogenic genetic diseases is specifically recommended for cases of serious diseases caused by a mutation. Its field of application is quite broad and is ideal for detecting all hereditary diseases with known mutation, of which the most common are:

  • Cystic fibrosis.
  • Fragile X syndrome.
  • Steinert myotonic dystrophy.
  • Tuberous sclerosis.
  • Polycystic kidney disease
  • Thalassemias

 

This list is not fixed and new diseases are constantly added (download here a complete list of hereditary diseases of known mutations). If you want to obtain more information about fertility and hereditary diseases or if you are a carrier of a specific family pathology, do not hesitate to schedule a consultation with our medical team. In Novafem we have the most modern advances in genetic diagnosis to offer a solution to these cases.

Preserve your fertility


In the Latin American fertility center Novafem, we offer fertility preservation techniques, which provide the possibility of postponing motherhood to all those women who wish to do so.

Recommended for:


  • Patients at risk of loss of ovarian function: patients diagnosed with cancer who will receive treatment with chemo or radiotherapy, autoimmune diseases requiring chemotherapy, bone marrow transplants or women at risk of repeated ovarian surgery, such as endometriosis.
  • Without medical indication or for social reasons: Women who decide to postpone their motherhood for various reasons or because their economic or work circumstances require it.