Sex of the baby
Discover the fetal sex in the tenth week of the pregnancy
When couples are following the road that leads to one of the most incredible and perfect events of nature developments, such as creating life from life, they are curious and want to know what their child’s sex is so they can start an emotional and affective relationship. This is the reason why Novafem, medical center of fertility and genetics in the company of Celagem, designed an examination called ‘fetal sexation in maternal peripheral blood’. This is a test that is able to give the couple information about the sex of their child. The test can be taken in the beginning of the tenth week of pregnancy with only a sample of peripheral blood from the mother. In the current medicine branche, the determination of the sex of the fetus is only possible through serial ultrasound controls or by a cytogenetic study from the 16th week of gestation.
This test bases its principles in the seventh week of gestation. This week there is an exchange of cells and nutrients between the mother and her child, cells that can be identified in the maternal blood, like the free DNA of a pregnant woman. The accurateness of this test is around 98%. Specifically for primigravid women (first pregnancies), or for a second pregnancy in the case that in its first pregnancy the child was a girl.
The test is designed to look for the presence of the Y chromosome (male chromosome) in maternal blood. After a pregnancy of which the result was a male, the DNA of the son can remain in the circulating blood for two more years. This can cause false values in the result of the test for a second pregnancy. Similarly, all women with pregnancy losses (abortions) over seven weeks of gestation, run the same risk of giving erroneous results, since the sex of their first pregnancy is not known.
These limitations forced Novafem, fertility and genetics medical center, to design a more complex test. This test not only has the potential to detect the sex of the baby from the tenth week, without presenting the limitations of the sexage in peripheral blood described above, but also offers more clinical information. The test has the ability to analyze in number, the autosomal and sexual chromosomes, responsible for 98% of the most common genetic diseases (aneuploidies), related to chromosomes 21, 13, 18, X and Y. This test has a sensitivity of 98%, and is called FISH in fetal erythroblasts in maternal peripheral blood.
In another order of ideas, it is well known by health specialists that there are microorganisms responsible for ruptures of premature membranes during pregnancy. Microorganisms that, some of them, can be diagnosed through conventional bacteriological cultures. In many countries of Europe and North America, research of four microorganisms that are involved in the rupture of premature membranes, is routinely researched during the controls of pregnancies in the third trimester. These microorganisms are Chlamydia Trachomatis, Ureaplasma Urealyticum, Mycoplasma Genitalium and Streptococcus Agalactiae (Beta hemolítico), which represent the microorganisms most frequently related to this phenomenon. This Multiplex is called premature membrane rupture profile.
Novafem, medical center of fertility and genetics, also has in its line of conventional tests, cytogenetic studies such as FISH in amniotic fluid and FISH in peripheral blood of the newborn. Which are widely disseminated tests in perinatal and puerperium studies.